M. Ratain: search on Z-Library

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1

Quantitative Analysis of Ethical Issues in Phase I Trials: A Survey Interview Study of 144 Advanced Cancer Patients

Christopher K. Daugherty, Donald M. Banik, Linda Janish and Mark J. Ratain

Journal:

IRB Ethics and Human Research

Year:

2000

File:

PDF, 4.21 MB

2000

2

Pharmacogenomics: will the promise be fulfilled?

Altman, Russ B., Kroemer, Heyo K., McCarty, Catherine A., Ratain, Mark J., Roden, Dan

Journal:

Nature Reviews Genetics

Year:

2010

Language:

english

File:

PDF, 239 KB

english, 2010

3

Evaluation of neuropathy in patients on suramin treatment

Betty Soliven, Upinder K. Dhand, Ken Kobayashi, Ravinder Arora, Barbara Martin, Michele V. Petersen, Linda Janisch, Nicholas J. Vogelzang, Everett E. Vokes, Mark J. Ratain

Journal:

Year:

1997

Language:

english

File:

PDF, 125 KB

english, 1997

4

Body Surface Area as a Determinant of Pharmacokinetics and Drug Dosing

Michael Sawyer, Mark J. Ratain

Journal:

Investigational New Drugs

Year:

2001

Language:

english

File:

PDF, 63 KB

english, 2001

5

The Role of Focus Group Interviews in Designing a Smoking Prevention Program

Giselle Heimann-Ratain, Molly Hanson, Stephen M. Peregoy

Journal:

Journal of School Health

Year:

1985

Language:

english

File:

PDF, 521 KB

english, 1985

6

Optimising the design of phase II oncology trials: The importance of randomisation

Mark J. Ratain, Daniel J. Sargent

Journal:

European Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 115 KB

english, 2009

7

Update on pharmacogenetics in cancer chemotherapy

F. Innocenti, M.J. Ratain

Journal:

European Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 116 KB

english, 2002

8

G6 Clinical activity observed in a phase I dose escalation trial of an oral c-met and ALK inhibitor, PF-02341066

E.L. Kwak, D.R. Camidge, J. Clark, G.I. Shapiro, R.G. Maki, M.J. Ratain, B. Solomon, Y. Bang, S. Ou, R. Salgia

Journal:

European Journal of Cancer Supplements

Year:

2009

Language:

english

File:

PDF, 48 KB

english, 2009

9

Phase I and pharmacological study of vinblastine by prolonged continuous infusion

Ratain, M.J., Vogelzang, N.J.

Journal:

Journal of Ethnopharmacology

Year:

1987

Language:

english

File:

PDF, 90 KB

english, 1987

10

Tumour heterogeneity in the clinic

Bedard, Philippe L., Hansen, Aaron R., Ratain, Mark J., Siu, Lillian L.

Journal:

Year:

2013

Language:

english

File:

PDF, 467 KB

english, 2013

11

5-Fluorouracil Pharmacokinetics: Causes for Variability and Strategies for Modulation in Cancer Chemotherapy

lyer, Lalitha, Ratain, Mark J.

Journal:

Cancer Investigation

Year:

1999

Language:

english

File:

PDF, 1.12 MB

english, 1999

12

The development of a financial toxicity patient-reported outcome in cancer: The COST measure

de Souza, Jonas A., Yap, Bonnie J., Hlubocky, Fay J., Wroblewski, Kristen, Ratain, Mark J., Cella, David, Daugherty, Christopher K.

Journal:

Year:

2014

Language:

english

File:

PDF, 205 KB

english, 2014

13

Polygenic inheritance of paclitaxel-induced sensory peripheral neuropathy driven by axon outgrowth gene sets in CALGB 40101 (Alliance)

Chhibber, A, Mefford, J, Stahl, E A, Pendergrass, S A, Baldwin, R M, Owzar, K, Li, M, Winer, E P, Hudis, C A, Zembutsu, H, Kubo, M, Nakamura, Y, McLeod, H L, Ratain, M J, Shulman, L N, Ritchie, M D, P

Journal:

The Pharmacogenomics Journal

Year:

2014

Language:

english

File:

PDF, 488 KB

english, 2014

14

Circadian variation in plasma 5-fluorouracil concentrations during a 24 hour constant-rate infusion

Fleming, Gini F, Schumm, Philip, Friberg, Greg, Ratain, Mark J, Njiaju, Uchenna O, Schilsky, Richard L

Journal:

Year:

2015

Language:

english

File:

PDF, 432 KB

english, 2015

15

Phase II Oncology Trials: Let's Be Positive

Journal:

Clinical Cancer Research

Year:

2005

Language:

english

File:

PDF, 50 KB

english, 2005

16

Design of Phase II Cancer Trials Using a Continuous Endpoint of Change in Tumor Size: Application to a Study of Sorafenib and Erlotinib in Non Small-Cell Lung Cancer

Karrison, T. G., Maitland, M. L., Stadler, W. M., Ratain, M. J.

Journal:

JNCI Journal of the National Cancer Institute

Year:

2007

Language:

english

File:

PDF, 105 KB

english, 2007

17

User Beware: We Need More Science and Less Art When Measuring Financial Toxicity in Oncology

de Souza, J. A., Yap, B., Ratain, M. J., Daugherty, C.

Journal:

Journal of Clinical Oncology

Year:

2015

Language:

english

File:

PDF, 60 KB

english, 2015

18

Genome-wide association studies of drug response and toxicity: an opportunity for genome medicine

Giacomini, Kathleen M., Yee, Sook Wah, Mushiroda, Taisei, Weinshilboum, Richard M., Ratain, Mark J., Kubo, Michiaki

Journal:

Nature Reviews Drug Discovery

Year:

2016

Language:

english

File:

PDF, 181 KB

english, 2016

19

Essential characteristics of pharmacogenomics study publications

Thorn, Caroline F., Whirl-Carrillo, Michelle, Hachad, Houda, Johnson, Julie A., McDonagh, Ellen M., Ratain, Mark J., Relling, Mary V., Scott, Stuart A., Altman, Russ B., Klein, Teri E.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 843 KB

english, 2018

20

Pharmacogenomic genotypes define genetic ancestry in patients and enable population-specific genomic implementation

Hernandez, Wenndy, Danahey, Keith, Pei, Xun, Yeo, Kiang-Teck J., Leung, Edward, Volchenboum, Samuel L., Ratain, Mark J., Meltzer, David O., Stranger, Barbara E., Perera, Minoli A., O’Donnell, Peter H.

Journal:

The Pharmacogenomics Journal

Year:

2019

Language:

english

File:

PDF, 1010 KB

english, 2019

21

Alternative dosing regimens for atezolizumab: right dose, wrong frequency

Goldstein, Daniel A., Ratain, Mark J.

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2019

File:

PDF, 489 KB

2019

22

Opportunities for using In Silico âBased Extended Dosing Regimens for Monoclonal Antibody Immune Checkpoint Inhibitors

Peer, Cody J., Goldstein, Daniel A., Goodell, Jennifer C., Nguyen, Ryan, Figg, William D., Ratain, Mark J.

Journal:

British Journal of Clinical Pharmacology

Year:

2020

File:

PDF, 931 KB

2020

23

GenomeâWide MetaâAnalysis Validates a Roless for S1PR1 in Microtubule Targeting AgentâInduced Sensory Peripheral Neuropathy

Chua, Katherina C., Xiong, Chenling, Ho, Carol, Mushiroda, Taisei, Jiang, Chen, Mulkey, Flora, Lai, Dongbing, Schneider, Bryan P., Rashkin, Sara R., Witte, John S., Friedman, Paula N., Ratain, Mark J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2020

File:

PDF, 16.72 MB

2020

24

Phase I study of escalating doses of mitoxantrone and paclitaxel with granulocyte-macrophage colony stimulating factor support

Gini F. Fleming, Linda Janisch, Nicholas J. Vogelzang, Everett E. Vokes, Mark J. Ratain

Journal:

Year:

1996

Language:

english

File:

PDF, 443 KB

english, 1996

25

Mineralocorticoid insufficiency due to suramin therapy

Ken Kobayashi, Roy E. Weiss, Nicholas J. Vogelzang, Everett E. Vokes, Linda Janisch, Mark J. Ratain

Journal:

Year:

1996

Language:

english

File:

PDF, 866 KB

english, 1996

26

Granulocyte-macrophage-colony stimulating factor in metastatic renal cell carcinoma : A phase II trial

Brian I. Rini, Walter M. Stadler, Ricardo T. Spielberger, Mark J. Ratain, Nicholas J. Vogelzang

Journal:

Year:

1998

Language:

english

File:

PDF, 87 KB

english, 1998

27

A Phase I study of raltitrexed and paclitaxel given every 3 weeks to patients with solid tumors

Everett E. Vokes, Boon C. Goh, Donna Bertucci, Nicholas J. Vogelzang, Sridhar Mani, Mark J. Ratain

Journal:

Year:

1999

Language:

english

File:

PDF, 66 KB

english, 1999

28

Flow cytometry in hairy cell leukemia before and during interferon alfa-2b therapy

Everett E. Vokes, Mitchell A. Bitter, Mark J. Ratain, Michael B. Prystowsky, Karen Daly, Harvey M. Golomb

Journal:

Year:

1987

Language:

english

File:

PDF, 549 KB

english, 1987

29

Prognostic variables in hairy cell leukemia after splenectomy as initial therapy

Mark J. Ratain, James W. Vardiman, Christopher M. Barker, Harvey M. Golomb

Journal:

Year:

1988

Language:

english

File:

PDF, 479 KB

english, 1988

30

A randomized study of inpatient versus outpatient continuous infusion chemotherapy for patients with locally advanced head and neck cancer

Everett E. Vokes, Richard L. Schilsky, Kyung E., Choi Pharmd, Dawn M. Magid, Carol M. Guarnieri, Susan M. Whaling, Mark J. Ratain, Ralph R. Weichselbaum, William R. Panje

Journal:

Year:

1989

Language:

english

File:

PDF, 716 KB

english, 1989

31

A phase I study of subcutaneous recombinant interleukin-2 and interferon alfa-2a

Mark J. Ratain, Edwin R. Priest, Linda Janisch, Nicholas J. Vogelzang

Journal:

Year:

1993

Language:

english

File:

PDF, 495 KB

english, 1993

32

A phase I study of intermittent infusion cladribine in patients with solid tumors

Ken Kobayashi, Nicholas J. Vogelzang, Sheila M. O'Brien, Richard L. Schilsky, Everett E. Vokes, Mark J. Ratain

Journal:

Year:

1994

Language:

english

File:

PDF, 621 KB

english, 1994

33

Prognostic factors for survival in patients treated in phase I clinical trials

Linda Janisch, Rosemarie Mick, Richard L. Schilsky, Nicholas J. Vogelzang, Sheila O'Brien, Michael Kuf, Mark J. Ratain

Journal:

Year:

1994

Language:

english

File:

PDF, 720 KB

english, 1994

34

Phase I study to evaluate multiple regimens of intravenous 5-fluorouracil administered in combination with weekly gemcitabine in patients with advanced solid tumors : A potential broadly active regimen for advanced solid tumor malignancies

Sridhar Mani, Nicholas J. Vogelzang, Donna Bertucci, Walter M. Stadler, Richard L. Schilsky, Mark J. Ratain

Journal:

Year:

2001

Language:

english

File:

PDF, 95 KB

english, 2001

35

Rapid response to 2′-deoxycoformycin in advanced hairy cell leukemia after failure of interferons alpha and gamma

Barry C. Lembersky, Dr. Mark J. Ratain, Carol Westbrook, Harvey M. Golomb

Journal:

American Journal of Hematology

Year:

1988

Language:

english

File:

PDF, 221 KB

english, 1988

36

Clinical trials

Jill S. Ratain, Marc C. Hochberg

Journal:

Arthritis & Rheumatism

Year:

1990

Language:

english

File:

PDF, 880 KB

english, 1990

37

Accuracy of creatinine clearance in measuring glomerular filtration rate in patients with systemic lupus erythematosus without clinical evidence of renal disease

Jill S. Ratain, Michelle Petri, Marc C. Hochberg, David B. Hellmann

Journal:

Arthritis & Rheumatism

Year:

1990

Language:

english

File:

PDF, 345 KB

english, 1990

38

Weekly, high-dose paclitaxel in advanced lung carcinoma : A Phase II study with pharmacokinetics by the Cancer and Leukemia Group B

Wallace Akerley, James E. Herndon, Merrill J. Egorin, Alan P. Lyss, Hedy L. Kindler, Dianne M. Savarese, Carol A. Sherman, D. Marc Rosen, Donna Hollis, Mark J. Ratain, Mark R. Green

Journal:

Year:

2003

Language:

english

File:

PDF, 92 KB

english, 2003

39

A Phase II trial of suramin monthly × 3 for hormone-refractory prostate carcinoma

Nicholas J. Vogelzang, Theodore Karrison, Walter M. Stadler, Juan Garcia, Helene Cohn, John Kugler, Thomas Troeger, Leonard Giannone, Rose Arrieta, Mark J. Ratain, Everett E. Vokes

Journal:

Year:

2004

Language:

english

File:

PDF, 87 KB

english, 2004

40

Quality of life impact of three different doses of suramin in patients with metastatic hormone-refractory prostate carcinoma : Results of Intergroup 0159/Cancer and Leukemia Group B 9480

Tim A. Ahles, James E. Herndon II, Eric J. Small, Nicholas J. Vogelzang, Alice B. Kornblith, Mark J. Ratain, Walter Stadler, David Palchak, M. Ernest Marshall, George Wilding, Daniel Petrylak, Jimmie

Journal:

Year:

2004

Language:

english

File:

PDF, 86 KB

english, 2004

41

A phase I trial of pharmacologic modulation of irinotecan with cyclosporine and phenobarbital

INNOCENTI, F, UNDEVIA, S, RAMIREZ, J, MANI, S, SCHILSKY, R, VOGELZANG, N, PRADO, M, RATAIN, M

Journal:

Clinical Pharmacology & Therapeutics

Year:

2004

Language:

english

File:

PDF, 174 KB

english, 2004

42

Genetic determinants of UGT1A1 inducibility

RAMIREZ, J, INNOCENTI, F, KOMOROSKI, B, MIRKOV, S, YODERGRABER, A, FACKENTHAL, D, DAS, S, SCHUETZ, E, STROM, S, RATAIN, M

Journal:

Clinical Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 56 KB

english, 2005

43

In vitro glucuronidation of prednisone

INNOCENTI, F, YODERGRABER, A, RAMIREZ, J, RATAIN, M

Journal:

Clinical Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 55 KB

english, 2005

44

Role of HNF-1? in the regulation of UGT1A1, UGT1A9 and UGT2B7 MRNA expression

MIRKOV, S, INNOCENTI, F, LIU, W, CHEN, P, RAMIREZ, J, UNDEVIA, S, DAS, S, RATAIN, M

Journal:

Clinical Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 55 KB

english, 2005

45

Inhibition of SN-38 glucuronidation by ketoconazole

YONG, W, RAMIREZ, J, INNOCENTI, F, RATAIN, M

Journal:

Clinical Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 57 KB

english, 2005

46

UGT1A1 and UGT1A9 variants affect thyroxine glucuronidation in human livers

YODERGRABER, A, INNOCENTI, F, RAMIREZ, J, CHEN, P, DAS, S, RATAIN, M

Journal:

Clinical Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 57 KB

english, 2005

47

Drug-metabolizing enzymes: Evidence for clinical utility of pharmacogenomic tests

ANDERSSON, T, FLOCKHART, D, GOLDSTEIN, D, HUANG, S, KROETZ, D, MILOS, P, RATAIN, M, THUMMEL, K

Journal:

Clinical Pharmacology & Therapeutics

Year:

2005

Language:

english

File:

PDF, 429 KB

english, 2005

48

A pharmacogenetic study on UDP-glucuronosyltransferase 2B7 in human livers.

Innocenti, F., Das, S., Chandler, J.W., Ramirez, J., Cooke, E.J., Ratain, M.J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2003

Language:

english

File:

PDF, 128 KB

english, 2003

49

Pharmacogenetics of flavopiridol, glucuronidation

Desai, A., Grimsley, C., Innocenti, F., Kuttob-Boulos, H., Ramirez, J., Rienzo, A. Di, Ratain, M. J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2003

Language:

english

File:

PDF, 127 KB

english, 2003

50

Use of CPT-11 as an in vitro phenotypic probe for CYP3A4/CYP3A5 activity

Ramirez, J., Innocenti, F., Rivory, L. P., Relling, M. V., Schuetz, E. G., Ratain, M. J.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2003

Language:

english

File:

PDF, 132 KB

english, 2003

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